Sylabus
1. Syndromology a symptomatology - Introduction
2. Diagnosis
3. Amelogenesis imperfecta, dentinogenesis imperfecta and osteogenesis imperfecta- symptomatology and syndromology
4. Families with multiple teeth retention
5. Haydu - Cheney syndrome
6. Prenatal diagnostics, syndromology a symptomatology amniocentesis and ultrasound, fetal echocardiography
7. Pachydermoperiostosis
8. Congenital spine deformities and rare syndromes
9. Bone and tooth dysplasias, oligodontia, hypodontia and anodontia; celidocranial dysplasia and low bone dnesity, biomechanice and clinical aspects; mucopolysaccharidoses and oligosaccharidoses, multiple cartilagenous exostoses, enchondromatosis, osteopetrosis and pycnodysostosis; Exomphalos-Macroglossia-Gigantism Syndrome, Parkes - Weber - Klippel - Trenaunay syndrome, hemihypertrophy aand asymetry, genetic consultation
10. Goldenhar syndrome and related syndromes, abnormal vertebral segmentation, Klippel -Feil anomaly, Jarcho - Levin syndrome, facioauriculovertebral spectrum comprising spectrum hemifacial microsomia,VACTERL, VATER, NTD, anencephaly, ecephalocoele, Poland-Moebius syndrome
11. Rheumatology and genetics
12. Haematology and genetics
13. Basocellular nevus syndrome
14. Arthrogryposis multiplex congenita.
15. Duchenne myopathyand its prenatal diagnostics
16. Pierre- Robin anomaly
17. Cerebrocostomandibular syndrome.
18. Syndromology of situs viscerum inversus.
Anotace
The subject aims at mastering selected genetics principles in stomatology. Genealogy, types of inheritance, monogenic traits, multifactorial inheritance.
Structure and function of chromosomes, karyotype. Numerical and structural aberrations.
Mutations, mutagens, molecular basis of inherited disease. Teratogenesis, inborn developmental diseaes, oncogenetics.
Genetic counselling. Genealogical analysis, counselling for hereditary diseases and syndromes of the orofacial area.