Syllabus
Teachers Prof. Stanislav Micuda, M.D., Ph.D. Assoc. Prof. Martin Štěrba, PharmDr., Ph.D. Assoc. Prof. Jaroslav Chladek, M.Sc., Ph.D. Jiri Grim, M.D., Ph.D. Assoc. Prof. Miroslav Solař, M.D., Ph.D. Lectures
1. Clinical oncology.2. Clinical pharmacology of biological drugs.3. Clinical pharmacology of heart failure.4. Introduction. The role of genetic polymorphism.5. Drug dosage in liver and kidney disease.6. Dosage regimen prediction based on the pharmacokinetic principle: therapeutic drug monitoring (TDM) and its usage in pharmacotherapy.
6.1. Demonstration and practical exercises.7. Adverse effects of drugs, Drug-drug interactions.
7.1. Overview, case reports.8. Clinical pharmacology of anticoagulant agents.
8.1. Case reports.9. Analgesics and antibiotics.10. Drugs in pregnancy and breastfeeding. Practical courses & seminars
1. Clinical oncology.2. Clinical pharmacology of biological drugs.3. Clinical pharmacology of heart failure.4. Introduction. The role of genetic polymorphism.5. Drug dosage in liver and kidney disease.6. Dosage regimen prediction based on the pharmacokinetic principle: therapeutic drug monitoring (TDM) and its usage in pharmacotherapy.
6.1. Demonstration and practical exercises.7. Adverse effects of drugs, Drug-drug interactions.
7.1. Overview, case reports.8. Clinical pharmacology of anticoagulant agents.
8.1. Case reports.9. Analgesics and antibiotics.10. Drugs in pregnancy and breastfeeding.
Annotation
Clinical pharmacology supports the rational use of drugs in humans to enhance the therapeutic effect and reduce side effects. Therefore, teaching this subject builds on the knowledge of basic pharmacology acquired during the study of the subjects Pharmacology I and II with the implication of evidence-based medicine principles.
The student will be introduced to the possibilities of therapy optimization using: therapeutic monitoring, pharmacogenetics, bioindicators, pharmacoepidemiology, drug adherence, and analysis of pharmacotherapeutic complications. Pharmacotherapy for pain, heart failure, thromboembolic complications, cancer, and infectious diseases will be discussed.
Practical teaching is oriented towards the use of acquired knowledge to solve specific pharmacotherapeutic situations that can be observed in clinical practice.