Sylabus
Lecturers: prof. PharmDr. Emil Rudolf, Ph.D. prof. MUDr. Martina Řezáčová, Ph.D. doc. MUDr. Alena Stoklasová, CSc. doc. RNDr. Radim Havelek, Ph.D.
RNDr. Jana Nekvindová, Ph.D.
Lectures:
Oxidative stress.
Pathobiology of cell death, intracellular communication.
Cell cycle and programmed cell death.
Cellular strategy in response to DNA damage.
Epigenetics. Credit test.
Anotace
The aim of this subject is to provide deeper insight into the intracellular events and signalling involved in cell death and proliferation, cell damage induction and prevention/response and related regulatory events on molecular level. The knowledge is applied to carcinogenesis, diagnostics and treatment of cancers.