Syllabus
Lectures
Drug Identification
Detection of drugs using physical constants, physicochemical methods (spectral, separational methods) and chemical methods
Group and selective reactions of individual structural types of drugs of important pharmacotherapeutic groups (analgesics-antipyretics, analgesics-anodynes, sedatives, anaesthetics, hypnotics, psychopharmaceuticals, analeptics, local anaesthetics, myorelaxants,etc.)
Tests on the purity of drugs (chemical tests chromatographic and spectral methods)
Determination of drug content (Pharmacopoeia Methods of Quantitative Analysis) APIs and Medicinal Products
Stability studies of pharmaceuticals
Development of methods for drug analysis
Chiral analysis
Seminars and Practical training
Analytical evaluation of pharmaceuticals using pharmacopoeia
Identification of the drug using physico-chemical constants, chemical reactions, physicochemical methods
Tests on the purity of drugs (chemical evidence of impurities, evidence of impurities or degradation products by chromatographic and spectral methods)
Determination of drug content (pharmacopoeial methods of quantitative analysis), APIs, medicinal products, bioassay
Lectures
Drug Identification
Detection of drugs using physical constants, physicochemical methods (spectral, separational methods) and chemical methods
Group and selective reactions of individual structural types of drugs of important pharmacotherapeutic groups (analgesics-antipyretics, analgesics-anodynes, sedatives, anaesthetics, hypnotics, psychopharmaceuticals, analeptics, local anaesthetics, myorelaxants,etc.)
Tests on the purity of drugs (chemical tests chromatographic and spectral methods)
Determination of drug content (Pharmacopoeia Methods of Quantitative Analysis) APIs and Medicinal Products
Stability studies of pharmaceuticals
Development of methods for drug analysis
Chiral analysis
Seminars and Practical training
Analytical evaluation of pharmaceuticals using pharmacopoeia
Identification of the drug using physico-chemical constants, chemical reactions, physicochemical methods
Tests on the purity of drugs (chemical evidence of impurities, evidence of impurities or degradation products by chromatographic and spectral methods)
Determination of drug content (pharmacopoeial methods of quantitative analysis), APIs, medicinal products, bioassay
Annotation
The structure of drug is the key point for the choice of the appropriate analytical technique.
The subject Analysis of chemical drugs provides theoretical and practical knowledge concerning the principles of quality assurance, safety and efficacy of pharmaceuticals. The course is baased not only on the current Czech and European Pharmacopoeia but it reflects also other modern pharmacopoeial monographs (e.g.The United States Pharmacopoeia). It also addresses other areas such as drug analysis in biological materiál, etc.