Syllabus
Předmět je zaměřen na technologické postupy formulace a výroby lékových forem, včetně úpravy tuhé fáze, separačních postupů, mísení a homogenizace, sterilizace, produkce vody vysoké čistoty; automatizační techniky ve farmaceutické výrobě a zásad správné výrobní praxe.
Annotation
Active pharmaceutical ingredients are transformed into appropriate dosage forms by special technological procedures using pharmaceutical excipients. The pharmaceutical manufacturing processed include physical and chemical processes and can be divided into a series of unit operations, namely particle size reduction (milling, micronization), separation procedures (sieving, drying, lyophilisation, dissolution, extraction, filtration, centrifugation) and homogenisation procedures (mixing of liquid, semi-solid and solid materials).
Besides these basic operations, also special production procedures typical at particular dosage forms are applied: granulation, tablet pressing, coating, sterilization, and formulation processes of novel pharmaceutical dosage forms: coacervation, extrusion, spheronization, and others.