Differential scan calorimetry (DSC)
- characterization of biodegradable polymers by DSC (determination of glass transition temperature T_g)
- polymers plasticization
- influence of the plasticizer type and concentration on T_g
- drug incorporation into the polymer (fusion method, plasticization method, solvent method)
- thermal analyses of solid polymeric dispersions
Pycnometric density of solids, porosimetry
- determination of tablet´s excipients density
- determination of tableting materials density
- determination of density and porosity of tablets in dependence on compression pressure
Determination of surface tension of liquids
- determination of surface tension of water
- determination of surface tension of surfactant solutions (cationic, anionic and nonionic)
Rheological evaluation of pharmaceutical preparations
- analysis of rheogram by appropriate models
- characterization of semi-solid preparations by Herschel-Bulkely model (coefficient of consistency and flow behaviour)
- thixotropy characterization of the pharmaceutical preparations
- influence of the pharmaceutical preparations composition and technology of compounding on rheological characteristics
Fluid bed granulation
- influence of process parameters on the quality of granulates
- preparing of a granulate and its evaluation
Spray drying
- influence of process parameters on the quality of a dried product
- evaluation of the spray dried product
Evaluation of the compressibility of tabletting materials and the effect of lubricants
- evaluation of the energetic profile of dry binders and directly compressible tabletting materials
- evaluation of the compactibility of dry binders and directly compressible tabletting materials by tensile strength of tablets
- evaluation of the lubricant effect in tabletting materials
Dissolution tests
- determination of active ingredients dissolution profile released from prolonged release tablets
- comparison of basket, paddle and flow- through cell dissolution methods
- influence of dissolution test´s settings on dissolution profiles