Detailed information about lectures, seminars and practicals are available at http://vyuka.lf3.cuni.cz/

Courses of the winter semester

Courses of the summer semester

The following list of lectures sumarizes topics from which test questions are randomly generated (see Requirements for the exam):

Course 1 - Cell structure and heredity

History of Life on Earth
Structure of prokaryotic cell
Genetics of prokaryotes
Structure of eukaryotic cell, organelles
Composition of intracellular fluid, pH
Laboratory analytical methods
Basic building blocks of cells
Structure and properties of proteins
Protein functions
Cytoskeleton
Overview of tissues
Epithelial tissues I (classification)
Structure of nucleic acids
Genetic code, genes, genome
Structure and function of cell nucleus, chromatin
Chromosomal basis of heredity
Origin of genetic variability
Principles of heredity, Mendelian principles
Gene linkage
Variability and changes of genetic information, mutations I
Variability and changes of genetic information, mutations II
Genetic determination of sex
Monogenic traits and disorders
Gene interactions
Multifactorial, polygenic traits and disorders
Phenotypes, genotypes, population genetics
Cytogenetics I – numerical chromosomal abnormalities
Cytogenetics II – structural chromosomal aberrations
Differences from Mendelian heredity – imprinting, dynamic mutations
Methods of chromosomal study, postnatal and prenatal cytogenetic diagnosis
Genetics in medicine, genetic counselling, prevention and treatment of genetic disorders
Structure and function of membranes
Transport across membranes, membrane potential
Intracellular transport of substances
Extracellular matrix, cell adhesion and cell junctions
Biotechnology, gene manipulations and gene therapy
Special methods of histology to distinguish tissues and cells
Methods of protein analysis I

Course 2 - Cell metabolism and specialisation

Course 3 - Cell signalling and immunity

Course 4 - Cell cycle and development