Block I: basic concepts in speciation and case study of a hybridization barrier, the triploid block

· Week 1. Lecture: Introduction to speciation and hybridization barriers; no practical class.

· Week 2. Lecture: Postzygotic barriers, Bayeson-Dobzhansky-Müller incompatibilities, genomic conflicts; no practical class.

· Week 3. Lecture: Knowledge consolidation I: group work on the concept of species; 4 hours practical class: reminders on R.

· Week 4. Lecture: Polyploid speciation, triploid block; no practical class.

· Week 5. Lecture: Transcriptomics, a method to understand the functional basis of hybridization barriers; 4 hours practical class: Transcriptomics of a hybridization barrier, the triploid block.

Block II: the population genomics of speciation, or how allele frequency changes lead to hybridization barriers

· Week 6. Lecture: Methodologies and concepts in population genomics I; no practical class.

· Week 7. Lecture: Methodologies and concepts in population genomics II; no practical class.

· Week 8. Lecture: Knowledge consolidation II, essay writing on a case study: the population genomics of speciation by domestication; no practical class.

· Week 9. Lecture: Genotype-phenotype associations, a method to discover speciation genes; 4 hours practical class: Hybrid necrosis in Capsella. Revealing the genetic basis using a QTL approach.

Block III: gene flow, the other side of the speciation coin

· Week 10. Lecture: Gene flow, the rule rather than the exception of speciation; no practical class.

· Week 11. Lecture: Evolutionary consequences of gene flow between species: hybrid speciation, adaptive introgression; no practical class.

· Week 12. Lecture: A method to detect gene flow; 4 hours practical class: Detecting gene flow between species.