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CELLS
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RNDr. Michaela Čermáková Ph.D.
Academic staff at Faculty of Science
2 classes
35 publications
Classes
class
Seminar for Bachelor Thesis
MC250S05 |
Faculty of Science
class
Seminar for Diploma Thesis
MC250S06 |
Faculty of Science
Publications
publication
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
2017 |
Faculty of Science
publication
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice
2016 |
Faculty of Science
publication
Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation
2015 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b(5)
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases
2012 |
Faculty of Science, Second Faculty of Medicine
publication
Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA
2008 |
Faculty of Science
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science
publication
Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
2018 |
Faculty of Science
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