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enzyme inhibition
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RNDr. Michaela Čermáková Ph.D.
Academic staff at Faculty of Science
2 classes
35 publications
Classes
class
Seminar for Bachelor Thesis
MC250S05 |
Faculty of Science
class
Seminar for Diploma Thesis
MC250S06 |
Faculty of Science
Publications
publication
Modulation of xenobiotic conjugation enzymes by dihydromyricetin in rats
2017 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science
publication
Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
2018 |
Faculty of Science
publication
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
2017 |
Faculty of Science
publication
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice
2016 |
Faculty of Science
publication
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
2016 |
Faculty of Science
publication
Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine
2016 |
Faculty of Science
publication
Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)
2016 |
Faculty of Science
publication
Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
2016 |
Faculty of Science
publication
NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1
2016 |
Faculty of Science
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