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human carcinogen
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RNDr. Michaela Čermáková Ph.D.
Academic staff at Faculty of Science
2 classes
35 publications
Classes
class
Seminar for Bachelor Thesis
MC250S05 |
Faculty of Science
class
Seminar for Diploma Thesis
MC250S06 |
Faculty of Science
Publications
publication
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
2017 |
Faculty of Science
publication
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
2016 |
Faculty of Science
publication
Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine
2016 |
Faculty of Science
publication
NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1
2016 |
Faculty of Science
publication
NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
2016 |
Faculty of Science
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b(5)
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes
2012 |
Faculty of Science
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science
publication
Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
2018 |
Faculty of Science
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