Classes
Publications
- The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung2013 | Faculty of Science
- The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice2013 | Faculty of Science
- Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases2012 | Faculty of Science, Second Faculty of Medicine
- Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma2011 | Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
- Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy2011 | Faculty of Science
- Role of cytochromes P450 and peroxidases in metabolism of the anticancer drug ellipticine: additional evidence of their contribution to ellipticine activation in rat liver, lung and kidney2010 | Faculty of Science
- Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse +12008 | Faculty of Science
- Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine2019 | Faculty of Science
- Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice2018 | Faculty of Science
- Modulation of xenobiotic conjugation enzymes by dihydromyricetin in rats2017 | Faculty of Science, Faculty of Pharmacy in Hradec Králové
Loading network view...