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interferon genes
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Mgr. Gabriel Birkuš Ph.D.
External academic staff at Central Library of Charles University
14 publications
Publications
publication
Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells
2023 |
Central Library of Charles University, Faculty of Science
publication
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
2022 |
Central Library of Charles University, Faculty of Science, Faculty of Physical Education and Sport
publication
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential
2022 |
Central Library of Charles University, Faculty of Science
publication
STING Agonist-Mediated Cytokine Secretion Is Accompanied by Monocyte Apoptosis
2022 |
Central Library of Charles University, Faculty of Science
publication
Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory
2021 |
Central Library of Charles University, Faculty of Science
publication
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-di(2'F,2'dAMP)
2021 |
Central Library of Charles University, Faculty of Science
publication
Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
2021 |
Central Library of Charles University, Faculty of Science
publication
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein
2021 |
Central Library of Charles University
publication
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
2019 |
Central Library of Charles University, Faculty of Science
publication
Development and Characterization of a Chronic Hepatitis B Murine Model With a Mutation in the START Codon of an HBV Polymerase
2023 |
Central Library of Charles University, Faculty of Science, Faculty of Physical Education and Sport
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