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CYP
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prof. RNDr. Petr Hodek CSc.
Academic staff at Faculty of Science
4 classes
234 publications
Classes
class
Advanced practical course in biochemistry II
MC250C08 |
Faculty of Science
class
Enzymology
+1
MC250P01 |
Faculty of Science
class
Biochemistry I
MC250P03C |
Faculty of Science
Publications
publication
Photo-cytochrome b(5) - A New Tool to Study the Cytochrome P450 Electron-transport Chain
2013 |
Faculty of Science
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens
2011 |
Faculty of Science
publication
The binding affinity of carcinogenic N-nitrosodimethylamine and N-nitrosomethylaniline to cytochromes P450 2B4, 2E1 and 3A6 does not dictate the rate of their enzymatic N- demethylation.
2010 |
Faculty of Science
publication
Mapping of cytochrome P4502B4 substrate binding sites by photolabile probe 3-azidiamantane: Identification of putative substrate access regions
2007 |
Faculty of Science
publication
Reductive activation of environmental pollutants 3-nitrobenzanthrone and 2-nitrobenzanthrone
2007 |
Faculty of Science
publication
Oxidation of ellipticine by human and rat cytochromes P450 correlates with its binding to DNA
2007 |
Faculty of Science
publication
Kinetics of ellipticine oxidation by cytochromes P450 1A1 and 1A2 reconstituted with NADPH:cytochrome P450 reductase
2007 |
Faculty of Science
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