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prof. RNDr. Petr Hodek CSc.
Academic staff at Faculty of Science
4 classes
234 publications
Classes
class
Advanced practical course in biochemistry II
MC250C08 |
Faculty of Science
class
Enzymology
+1
MC250P01 |
Faculty of Science
class
Biochemistry I
MC250P03C |
Faculty of Science
Publications
publication
Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I)
2013 |
Faculty of Science
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
The binding affinity of carcinogenic N-nitrosodimethylamine and N-nitrosomethylaniline to cytochromes P450 2B4, 2E1 and 3A6 does not dictate the rate of their enzymatic N- demethylation.
2010 |
Faculty of Science
publication
Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: Possible role of Arg 133 in modulation of function and activity of this enzyme
2008 |
Faculty of Science
publication
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA
2008 |
Faculty of Science
publication
Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid
2008 |
Faculty of Science
publication
Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 ? similarity between human and rat enzymes
2008 |
Faculty of Science
publication
Structural analysis of cytochromes P450 shows differences in flexibility of heme 2-and 4-vinyls
2007 |
Faculty of Science
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