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Ellipticine
Person
Class
Person
Publication
Programmes
prof. RNDr. Petr Hodek CSc.
Academic staff at Faculty of Science
4 classes
234 publications
Classes
class
Advanced practical course in biochemistry II
MC250C08 |
Faculty of Science
class
Enzymology
+1
MC250P01 |
Faculty of Science
class
Biochemistry I
MC250P03C |
Faculty of Science
Publications
publication
Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I)
2013 |
Faculty of Science
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
Miniaturize electrochemical systems in the detection of an anticancer agents interaction with DNA
2008 |
Faculty of Science
publication
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA
2008 |
Faculty of Science
publication
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism
2007 |
Faculty of Science
publication
The anticancer drug ellipticine is an inducer of rat NAD(P)H : Quinone oxidoreductase
2007 |
Faculty of Science
publication
Studies with the hepatic NADPH:cytochrome P450 reductase null mouse reveal the role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine
2007 |
Faculty of Science
publication
Oxidation of ellipticine by human and rat cytochromes P450 correlates with its binding to DNA
2007 |
Faculty of Science
publication
Kinetics of ellipticine oxidation by cytochromes P450 1A1 and 1A2 reconstituted with NADPH:cytochrome P450 reductase
2007 |
Faculty of Science
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