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NADPH
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prof. RNDr. Petr Hodek CSc.
Academic staff at Faculty of Science
4 classes
234 publications
Classes
class
Advanced practical course in biochemistry II
MC250C08 |
Faculty of Science
class
Enzymology
+1
MC250P01 |
Faculty of Science
class
Biochemistry I
MC250P03C |
Faculty of Science
Publications
publication
Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I)
2013 |
Faculty of Science
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
Mapping of interaction between cytochrome P450 2B4 and cytochrome b5: the first evidence of two mutual orientations
2012 |
Faculty of Science
publication
Close look at cytochrome P450-b5 catalytic complex
2011 |
Faculty of Science
publication
The binding affinity of carcinogenic N-nitrosodimethylamine and N-nitrosomethylaniline to cytochromes P450 2B4, 2E1 and 3A6 does not dictate the rate of their enzymatic N- demethylation.
2010 |
Faculty of Science
publication
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA
2008 |
Faculty of Science
publication
Studies with the hepatic NADPH:cytochrome P450 reductase null mouse reveal the role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine
2007 |
Faculty of Science
publication
Reductive activation of environmental pollutants 3-nitrobenzanthrone and 2-nitrobenzanthrone
2007 |
Faculty of Science
publication
Kinetics of ellipticine oxidation by cytochromes P450 1A1 and 1A2 reconstituted with NADPH:cytochrome P450 reductase
2007 |
Faculty of Science
publication
Cytochromes P450 reconstituted with NADPH:P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes
2006 |
Faculty of Science
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