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adduct formation
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prof. RNDr. Petr Hodek CSc.
Academic staff at Faculty of Science
4 classes
234 publications
Classes
class
Advanced practical course in biochemistry II
MC250C08 |
Faculty of Science
class
Enzymology
+1
MC250P01 |
Faculty of Science
class
Biochemistry I
MC250P03C |
Faculty of Science
Publications
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity
2008 |
Faculty of Science
publication
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism
2007 |
Faculty of Science
publication
Oxidation of ellipticine by human and rat cytochromes P450 correlates with its binding to DNA
2007 |
Faculty of Science
publication
Comparison of the cytotoxicity of and DNA adduct formation by the anticancer drug ellipticine in human breast adenocarcinoma, leukemia and neuroblastoma cells
2007 |
Faculty of Science
publication
The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib
2022 |
Faculty of Science
publication
Nanomedicine of tyrosine kinase inhibitors
2021 |
Faculty of Science, Second Faculty of Medicine
publication
Apoferritin/vandetanib association is long-term stable but does not improve pharmacological properties of vandetanib
2021 |
Faculty of Science, Second Faculty of Medicine
publication
Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro
2021 |
Faculty of Science
publication
Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats
2021 |
Faculty of Science
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