Publications
- Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents2015 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties2014 | Faculty of Pharmacy in Hradec Králové
- Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: Novel iron chelators with selective antiproliferative action2012 | Faculty of Pharmacy in Hradec Králové
- Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine2022 | Faculty of Pharmacy in Hradec Králové
- Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase II beta inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline2019 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Cardioprotective Potential of Iron Chelators and Prochelators2019 | Faculty of Pharmacy in Hradec Králové
- Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials2019 | Faculty of Pharmacy in Hradec Králové
- 2,6-Dihydroxybenzaldehyde analogues of the iron chelator salicylaldehyde isonicotinoyl hydrazone: Increased hydrolytic stability and cytoprotective activity against oxidative stress2018 | Faculty of Pharmacy in Hradec Králové
- Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite2017 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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