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Inhibition
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PharmDr. Ondřej Holas Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
2 classes
53 publications
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class
Physical Principles of Dosage Forms
+1
GAPS308 |
Faculty of Pharmacy in Hradec Králové
Publications
publication
3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Science
publication
Stilbene compound trans-3,4,5,4'-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Unexpected Effects of Propiconazole, Tebuconazole, and Their Mixture on the Receptors CAR and PXR in Human Liver Cells
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation
2017 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Alzheimer's disease drugs - In Vitro comparison of cholinesterase inhibition and beta-amyloid modulation
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Monooxime bispyridinium reactivators bearing xylene linker synthesis and in vitro evaluation on model of organophosphate-inhibited acetylcholinesterase
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Enantiospecific effects of chiral drugs on cytochrome P450 inhibition in vitro
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Mycobacterium tuberculosis enoyl-acyl carrier protein reductase inhibitors as potential antituberculotics: development in the past decade
2015 |
Faculty of Pharmacy in Hradec Králové
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