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Ligand binding sites
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Person
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prof. RNDr. Tomáš Obšil Ph.D.
Academic staff at Faculty of Science
2 study programmes
4 classes
111 publications
Study programme
programme
Physical Chemistry
+1
🇨🇿 PhD. |
Faculty of Science
Classes
class
Biophysical chemistry I
MC260P44 |
Faculty of Science
class
Biophysical chemistry II - experimental methods
MC260P45 |
Faculty of Science
class
Biophysical chemistry II - experimental methods - A
MC260P45A |
Faculty of Science
class
Physical Chemistry
MC260P52 |
Faculty of Science
Publications
publication
Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.
2004 |
Faculty of Science
publication
14-3-3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices
2023 |
Faculty of Science, Faculty of Mathematics and Physics, Central Library of Charles University
publication
Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex
2023 |
Faculty of Science
publication
Nedd4-2 binding to 14-3-3 modulates the accessibility of its catalytic site and WW domains
2022 |
Faculty of Science, Faculty of Mathematics and Physics, Central Library of Charles University
publication
FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA
2022 |
Faculty of Science, Central Library of Charles University
publication
Lengthening the Guanidine–Aryl Linker of Phenylpyrimidinylguanidines Increases Their Potency as Inhibitors of FOXO3-Induced Gene Transcription
2022 |
Faculty of Science, Central Library of Charles University
publication
Structural insights into the functional roles of 14-3-3 proteins
2022 |
Faculty of Science, Central Library of Charles University
publication
14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains
2021 |
Faculty of Science, Faculty of Physical Education and Sport, First Faculty of Medicine
publication
14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites
2021 |
Faculty of Science, Faculty of Mathematics and Physics, Central Library of Charles University
publication
Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions
2021 |
Faculty of Science, Central Library of Charles University
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