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blood-brain-barrier
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PharmDr. Lukáš Prchal Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
48 publications
Publications
publication
Novel D-2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment
2022 |
Central Library of Charles University
publication
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-D-Aspartate Receptor Antagonists
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
Huprine Y-Tryptophan heterodimers with potential implication to Alzheimer's disease treatment
2021 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine
publication
Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D-2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole
2021 |
Publication without faculty affiliation
publication
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile
2020 |
Publication without faculty affiliation
publication
Tacroximes: novel unique compounds for the recovery of organophosphorus-inhibited acetylcholinesterase
2019 |
Publication without faculty affiliation
publication
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
2024 |
Faculty of Science, First Faculty of Medicine, Third Faculty of Medicine
publication
Structure-Guided Design of N-Methylpropargylamino- Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
UHPLC-Orbitrap study of the first phase tacrine in vitro metabolites and related Alzheimer's drug candidates using human liver microsomes
2023 |
Faculty of Pharmacy in Hradec Králové
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