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PharmDr. Lukáš Prchal Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
48 publications
Publications
publication
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides
2022 |
Publication without faculty affiliation
publication
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
2022 |
Publication without faculty affiliation
publication
7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo
2021 |
Faculty of Pharmacy in Hradec Králové, Central Library of Charles University
publication
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
2021 |
Publication without faculty affiliation
publication
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease
2021 |
Publication without faculty affiliation
publication
Synthesis, antimicrobial effect and lipophilicity-activity dependence of three series of dichained N-alkylammonium salts
2019 |
Publication without faculty affiliation
publication
Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
2024 |
Faculty of Science, First Faculty of Medicine, Third Faculty of Medicine
publication
Structure-Guided Design of N-Methylpropargylamino- Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
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