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molecular aberrations
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MUDr. Diana Maláriková
Academic staff at First Faculty of Medicine
10 publications
Publications
publication
Concurrent tp53 and cdkn2a gene aberrations in newly diagnosed mantle cell lymphoma correlate with chemoresistance and call for innovative upfront therapy
2020 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Ibrutinib in mantle cell lymphoma: a real-world retrospective multi-center analysis of 77 patients treated in the Czech Republic
2023 |
First Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy
2023 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas
2022 |
First Faculty of Medicine, Second Faculty of Medicine, Faculty of Medicine in Pilsen, Faculty of Physical Education and Sport
publication
A high TP53 mutation burden is a strong predictor of primary refractory mantle cell lymphoma
2020 |
First Faculty of Medicine
publication
Cotargeting of BCL2 with venetoclax and MCL1 with S63845 is synthetically lethal in vivo in relapsed mantle cell lymphoma
2019 |
First Faculty of Medicine, Second Faculty of Medicine
publication
3,5,7-Substituted Pyrazolo[4,3-d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models
2019 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Effective doxorubicin-based nano-therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging
2018 |
First Faculty of Medicine
publication
Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement
2017 |
First Faculty of Medicine
publication
Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL
2017 |
First Faculty of Medicine
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