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In-Vivo
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PharmDr. Eduard Jirkovský Ph.D.
Academic staff at Faculty of Medicine in Hradec Králové
29 publications
Publications
publication
The effects of bisphenols on the cardiovascular system ex vivo and in vivo
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II beta Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane
2016 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Cardiac troponinsTranslational biomarkers in cardiology: Theory and practice of cardiac troponin high-sensitivity assays
2016 |
Faculty of Medicine in Hradec Králové
publication
Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity
2011 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
A Complex Methodological Approach for the Screening of Efficient and Safe Cobalt Chelators
2023 |
Faculty of Pharmacy in Hradec Králové
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