Publications
- Primary prevention of chronic anthracycline cardiotoxicity with ACE inhibitor is temporarily effective in rabbits, but benefits wane in post-treatment follow-up2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase II beta Interactions2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II beta Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline2019 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart2018 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane2016 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?2016 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Diagnostic window of cardiac troponin T on model of anthracycline-induced cardiomyopathy2016 | Faculty of Medicine in Hradec Králové
- Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo2015 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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