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dexrazoxane ICRF-187
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PharmDr. Eduard Jirkovský Ph.D.
Academic staff at Faculty of Medicine in Hradec Králové
29 publications
Publications
publication
Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase II beta Interactions
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II beta Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
The effects of bisphenols on the cardiovascular system ex vivo and in vivo
2023 |
Faculty of Pharmacy in Hradec Králové
publication
A Complex Methodological Approach for the Screening of Efficient and Safe Cobalt Chelators
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Primary prevention of chronic anthracycline cardiotoxicity with ACE inhibitor is temporarily effective in rabbits, but benefits wane in post-treatment follow-up
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
The effects of bisphenols on the cardiovascular system
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Systematic review of pharmacokinetics and potential pharmacokinetic interactions of flavonolignans from silymarin
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Silymarin Dehydroflavonolignans Chelate Zinc and Partially Inhibit Alcohol Dehydrogenase
2021 |
Faculty of Pharmacy in Hradec Králové
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