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C inhibitor
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Mgr. Radim Nencka Ph.D.
External academic staff at Central Library of Charles University
25 publications
Publications
publication
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors
2023 |
Faculty of Science, Central Library of Charles University
publication
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
2023 |
Faculty of Science, Central Library of Charles University
publication
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential
2022 |
Faculty of Science, Central Library of Charles University
publication
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold
2022 |
Faculty of Science, Central Library of Charles University
publication
High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses
2021 |
Central Library of Charles University
publication
Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication
2021 |
Central Library of Charles University
publication
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
2019 |
Faculty of Science, Central Library of Charles University
publication
The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors
2018 |
Central Library of Charles University
publication
Highly Selective Phosphatidylinositol 4-Kinase III beta Inhibitors and Structural Insight into Their Mode of Action
2015 |
Central Library of Charles University
publication
The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design
2015 |
Central Library of Charles University
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