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interferon genes
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Mgr. Radim Nencka Ph.D.
External academic staff at Central Library of Charles University
25 publications
Publications
publication
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential
2022 |
Faculty of Science, Central Library of Charles University
publication
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-di(2'F,2'dAMP)
2021 |
Faculty of Science, Central Library of Charles University
publication
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein
2021 |
Central Library of Charles University
publication
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
2019 |
Faculty of Science, Central Library of Charles University
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Central Library of Charles University, First Faculty of Medicine, Faculty of Pharmacy in Hradec Králové
publication
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors
2023 |
Faculty of Science, Central Library of Charles University
publication
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
2023 |
Faculty of Science, Central Library of Charles University
publication
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold
2022 |
Faculty of Science, Central Library of Charles University
publication
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses
2021 |
Faculty of Science, Central Library of Charles University
publication
High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses
2021 |
Central Library of Charles University
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