Předměty
Publikace
- Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems2020 | Přírodovědecká fakulta, 2. lékařská fakulta
- Tyrosine kinase inhibitors vandetanib, lenvatinib and cabozantinib modulate oxidation of an anticancer agent ellipticine catalyzed by cytochromes P450 in vitro2018 | Přírodovědecká fakulta
- Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)2016 | Přírodovědecká fakulta
- NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A12016 | Přírodovědecká fakulta
- Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions2014 | Přírodovědecká fakulta, Ústřední knihovna
- Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases2012 | Přírodovědecká fakulta, 2. lékařská fakulta
- The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib2022 | Přírodovědecká fakulta
- Apoferritin/vandetanib association is long-term stable but does not improve pharmacological properties of vandetanib2021 | Přírodovědecká fakulta, 2. lékařská fakulta
- Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes2021 | Přírodovědecká fakulta
- Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity2020 | Přírodovědecká fakulta
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