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DNA adducts
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Mgr. Radek Indra Ph.D.
Academic staff at Faculty of Science
3 classes
26 publications
Classes
class
Biochemistry
MC250P03B |
Faculty of Science
class
Molecular oncology
MC250P63 |
Faculty of Science
class
Biochemistry for IES
MO550P88 |
Faculty of Science
Publications
publication
Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
2021 |
Faculty of Science
publication
Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells
2019 |
Faculty of Science, Second Faculty of Medicine
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science
publication
The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro
2019 |
Faculty of Science
publication
Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
2018 |
Faculty of Science
publication
Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers
2018 |
Faculty of Science
publication
Cytochrome b(5) plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine
2017 |
Faculty of Science, Second Faculty of Medicine
publication
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
2017 |
Faculty of Science
publication
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice
2016 |
Faculty of Science
publication
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
2016 |
Faculty of Science
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