Předměty
Publikace
- The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib2022 | Přírodovědecká fakulta
- Apoferritin/vandetanib association is long-term stable but does not improve pharmacological properties of vandetanib2021 | Přírodovědecká fakulta, 2. lékařská fakulta
- Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems2020 | Přírodovědecká fakulta, 2. lékařská fakulta
- Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity2020 | Přírodovědecká fakulta
- Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation2019 | Přírodovědecká fakulta, 2. lékařská fakulta
- The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro2019 | Přírodovědecká fakulta
- Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers2018 | Přírodovědecká fakulta
- Tyrosine kinase inhibitors vandetanib, lenvatinib and cabozantinib modulate oxidation of an anticancer agent ellipticine catalyzed by cytochromes P450 in vitro2018 | Přírodovědecká fakulta
- The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice2016 | Přírodovědecká fakulta
- Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases2012 | Přírodovědecká fakulta, 2. lékařská fakulta
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