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drug-metabolizing enzyme
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PharmDr. Tomáš Zárybnický Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
8 publications
Publications
publication
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
2019 |
Faculty of Pharmacy in Hradec Králové, Third Faculty of Medicine
publication
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation
2023 |
Faculty of Pharmacy in Hradec Králové
publication
The Hepatotoxicity of Alantolactone and Germacrone: Their Influence on Cholesterol and Lipid Metabolism in Differentiated HepaRG Cells
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Imatinib-induced changes in the expression profile of microRNA in the plasma and heart of mice-A comparison with doxorubicin
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Medicine in Pilsen
publication
The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR
2019 |
Faculty of Pharmacy in Hradec Králové, Third Faculty of Medicine
publication
The metabolism of flubendazole in human liver and cancer cell lines
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Hepatotoxicity of monoterpenes and sesquiterpenes
2018 |
Faculty of Pharmacy in Hradec Králové
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