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doc. RNDr. Jiří Brynda CSc.
External academic staff at Central Library of Charles University
11 publications
Publications
publication
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery
2021 |
Faculty of Science, Central Library of Charles University
publication
Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog
2016 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University
publication
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors
2023 |
Faculty of Science, Central Library of Charles University
publication
Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction
2022 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University
publication
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
2022 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University
publication
Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase
2021 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University
publication
Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors
+1
2021 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University
publication
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads
2021 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University
publication
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors
2020 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University
publication
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
2019 |
Faculty of Science, Central Library of Charles University
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