Classes
Publications
- Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors2019 | Faculty of Pharmacy in Hradec Králové
- Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation2017 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure2023 | Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
- 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR)2023 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
- Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids2022 | Faculty of Pharmacy in Hradec Králové
- Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism2021 | Faculty of Pharmacy in Hradec Králové
- New total synthesis and structure confirmation of putative (+)-hyacinthacine C-3 and (+)-5-epi-hyacinthacine C-32021 | Faculty of Pharmacy in Hradec Králové
- The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling2018 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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