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PharmDr. Lucie Smutná Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
4 classes
17 publications
Classes
class
Principles of Dosimetry and Radiation Protection
+2
GAF214 |
Faculty of Pharmacy in Hradec Králové
class
Principles of Dosimetry and Radioation Protection
GB192 |
Faculty of Pharmacy in Hradec Králové
Publications
publication
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism
2021 |
Faculty of Pharmacy in Hradec Králové
publication
The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats
2017 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation
2016 |
Faculty of Pharmacy in Hradec Králové
publication
The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
publication
2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR)
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
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