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Molecular modeling
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PharmDr. Martin Andrš
External person at Faculty of Medicine in Hradec Králové
20 publications
Publications
publication
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1
2023 |
Faculty of Pharmacy in Hradec Králové
publication
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity
2015 |
Publication without faculty affiliation
publication
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment
2015 |
Publication without faculty affiliation
publication
7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies
2014 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
In silico library screening to find novel anticancer agent with chemosensitizing properties: focus on targeting ataxia telangiectasia and Rad3 related kinase
2024 |
Faculty of Medicine in Hradec Králové
publication
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer
2021 |
Publication without faculty affiliation
publication
Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy
2020 |
Faculty of Medicine in Hradec Králové
publication
Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
2020 |
Central Library of Charles University
publication
Novel quinazolin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity
2019 |
Faculty of Medicine in Hradec Králové
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