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Dr. Anselm Morell Garcia
Akademický pracovník na Farmaceutická fakulta v Hradci Králové
10 publikací
Publikace
publication
Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo
2021 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme
2020 |
Farmaceutická fakulta v Hradci Králové
publication
Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Inhibition of AKR1B10-mediated metabolism of daunorubicin as a novel off-target effect for the Bcr-Abl tyrosine kinase inhibitor dasatinib
2021 |
Farmaceutická fakulta v Hradci Králové
publication
Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism
2021 |
Farmaceutická fakulta v Hradci Králové
publication
Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors
2020 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Interactions of antileukemic drugs with daunorubicin reductases: could reductases affect the clinical efficacy of daunorubicin chemoregimens?
2020 |
Farmaceutická fakulta v Hradci Králové
publication
Bruton's Tyrosine Kinase Inhibitors Ibrutinib and Acalabrutinib Counteract Anthracycline Resistance in Cancer Cells Expressing AKR1C3
2020 |
Farmaceutická fakulta v Hradci Králové
publication
Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3
2019 |
Farmaceutická fakulta v Hradci Králové
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