Publications
- Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure2023 | Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
- Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis2023 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists2023 | Faculty of Pharmacy in Hradec Králové, Faculty of Science
- (E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Science
- Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System2021 | Faculty of Pharmacy in Hradec Králové
- 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Science
- Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Physical Education and Sport
- The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Stilbene compound trans-3,4,5,4'-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver2019 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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