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drug ellipticine
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RNDr. Lucie Bořek Dohalská Ph.D.
Academic staff at Faculty of Science
1 class
73 publications
Class
class
Biochemistry practise
MC250C34 |
Faculty of Science
Publications
publication
The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide
2004 |
Faculty of Science
publication
DNA adduct formation by the anticancer drug ellipticine and its hydroxy derivatives in human breast adenocarcinoma MCF-7 cells
2004 |
Faculty of Science
publication
Cytotoxicity if the anticancer drug ellipticine and its hydroxyderivates to MCF-7 human breast cancer cells: study on covalent binding to DNA
2003 |
Faculty of Science
publication
Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans
2003 |
Faculty of Science
publication
The interaction between the anticancer drug ellipticine and cytochromes P450 dictates its pharmacological efficiencies
2003 |
Faculty of Science
publication
Mechanism of DNA adduct formation by anticancer drug ellipticine activated by cytochromes P450 in vitro and in vivo
2003 |
Faculty of Science
publication
Anticancer drug ellipticine is oxidized by myeloperoxidase and lactoperoxidase
2003 |
Faculty of Science
publication
Rat cytochromes P450 are suitable model enzymes mimicking the metabolic activation of anticancer drug ellipticine in humans
2003 |
Faculty of Science
publication
Interaction of anticancer drug ellipticine with cytochromes P450
2002 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Anticancer drug ellipticine is oxidized by lactoperoxidase
2002 |
First Faculty of Medicine, Faculty of Mathematics and Physics
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