Publications
- Effects of novel 17 beta-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration2021 | First Faculty of Medicine
- Novel benzothiazole-based ureas as 17 beta-HSD10 inhibitors, a potential Alzheimer's disease treatment2019 | Publication without faculty affiliation
- Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment2017 | Publication without faculty affiliation
- 6-Benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17 beta-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation2017 | Publication without faculty affiliation
- Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17 beta-HSD10 modulators for Alzheimer's disease treatment2016 | Publication without faculty affiliation
- Development of submicromolar 17 beta-HSD10 inhibitors and their in vitro and in vivo evaluation2023 | First Faculty of Medicine
- Alzheimerova nemoc2020 | Faculty of Medicine in Hradec Králové
- Benzothiazolyl ureas are low micromolar and uncompetitive inhibitors of 17β-HSD10 with implications to Alzheimer's disease treatment2020 | Publication without faculty affiliation
- Mitochondriální enzym ABAD a jeho role v rozvoji a léčbě Alzheimerovy nemoci2020 | Publication without faculty affiliation
- 1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders2018 | First Faculty of Medicine
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