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HIV-1
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Person
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prof. RNDr. Jan Konvalinka CSc.
Academic staff at Faculty of Science
5 classes
164 publications
Classes
class
Molecular biology and genetics II
+1
MC250P16 |
Faculty of Science
class
Molecular Biology and Genetics II
MC250P16N |
Faculty of Science
class
Proteolysis and regulation of biological processes
MC250P39 |
Faculty of Science
class
Drug design and development
MC250P71 |
Faculty of Science
Publications
publication
Ion specific effects of alkali cations on the catalytic activity of HIV-1 protease
2013 |
Faculty of Science
publication
HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat
2011 |
Faculty of Science
publication
A reliable docking/scoring scheme based on the semiempirical quantum mechanical PM6-DH2 method accurately covering dispersion and H-bonding: HIV-1 protease with 22 ligands.
2010 |
Faculty of Science
publication
Ninety-nine is not enough: Molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region
2008 |
Faculty of Science
publication
Ninety Nine is Not Enough: Molecular Characterization of Inhibitor Resistant HIV-1 Protease Mutants with Insertions in the Flap Region.
2008 |
Faculty of Science
publication
Novel Substrate Based HIV-1 Protease Inhibitor Drug Resistance Mechanism.
2007 |
Faculty of Science
publication
Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants
2007 |
Faculty of Science
publication
On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 angstrom resolution
2006 |
Faculty of Science
publication
HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site
2006 |
Faculty of Science
publication
An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.
2003 |
Faculty of Science
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