Classes
Publications
- Inorganic polyhedral metallacarborane inhibitors of HIV protease: A new approach to overcoming antiviral resistance.2008 | Faculty of Science
- Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir.2008 | Faculty of Science
- Novel Substrate Based HIV-1 Protease Inhibitor Drug Resistance Mechanism.2007 | Faculty of Science
- Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis2007 | Faculty of Science
- Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer2006 | Faculty of Science
- On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 angstrom resolution2006 | Faculty of Science
- HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site2006 | Faculty of Science
- Long term analysis of the resistance development in HIV positive patients treated by protease inhibitors in the Czech Republic: correlation of the genotype and disease progression.2005 | Faculty of Science
- Homology modeling and SAR analysis of Schistosoma japonicum cathepsin D (SjCD) with statin inhibitors identifies a unique active site steric barrier of potential for the design of specific inhibitors.2005 | Faculty of Science
- Dual substrate and reaction specificity in mouse serine racemase: Identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the ß-eliminase activity.2005 | Faculty of Science
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