Publikace
- Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection2013 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- DNA topoisomerase II beta: A player in regulation of gene expression and cell differentiation2012 | Farmaceutická fakulta v Hradci Králové
- Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase II beta Interactions2021 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo2021 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation2021 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase II beta inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity2021 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II beta Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity2020 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline2019 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study2019 | Farmaceutická fakulta v Hradci Králové
- Detection and quantitation of iron in ferritin, transferrin and labile iron pool (LIP) in cardiomyocytes using Fe-55 and storage phosphorimaging2018 | Farmaceutická fakulta v Hradci Králové, 1. lékařská fakulta, Přírodovědecká fakulta
Loading network view...
