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PharmDr. Anna Jirkovská Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
37 publications
Publications
publication
Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II beta Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite
2017 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane
2016 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Comparison of clinically used and experimental iron chelators for protection against oxidative stress-induced cellular injury
2010 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Comparison of clinically used and experimental iron chelators for protection against oxidative stress-induced cellular injury
2010 |
Central Library of Charles University
publication
Role of iron in hydrogen peroxide- and tert-butyl hydroperoxide- induced cardiomyoblast cell death
Publication without faculty affiliation
publication
Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase II beta Interactions
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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