Publications
- Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase II beta Interactions2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase II beta inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Neonatal capsaicin administration impairs postnatal development of the cardiac chronotropy and inotropy in rats2016 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen, First Faculty of Medicine
- Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo2015 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury2014 | Faculty of Pharmacy in Hradec Králové
- In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity2011 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Synthesis and initial in vitro evaluations of novel antioxidant aroylhydrazone iron chelators with increased stability against plasma hydrolysis2011 | Faculty of Pharmacy in Hradec Králové
- Comparison of various iron chelators used in clinical practice as protecting agents against catecholamine-induced oxidative injury and cardiotoxicity2011 | Faculty of Pharmacy in Hradec Králové
- Iron chelation for prevention of catecholamine-induced cardiomyocyte toxicityPublication without faculty affiliation
- Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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