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catalysis
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RNDr. Milan Dejmek Ph.D.
External academic staff at Central Library of Charles University
18 publications
Publications
publication
Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells
2023 |
Faculty of Science, Central Library of Charles University
publication
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors
2023 |
Faculty of Science, Central Library of Charles University
publication
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
2023 |
Faculty of Science, Central Library of Charles University
publication
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
2022 |
Faculty of Science, Central Library of Charles University, Faculty of Physical Education and Sport
publication
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential
2022 |
Faculty of Science, Central Library of Charles University
publication
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold
2022 |
Faculty of Science, Central Library of Charles University
publication
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-di(2'F,2'dAMP)
2021 |
Faculty of Science, Central Library of Charles University
publication
Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication
2021 |
Central Library of Charles University
publication
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein
2021 |
Central Library of Charles University
publication
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
2019 |
Faculty of Science, Central Library of Charles University
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