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missense variant
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RNDr. Jan Hojný Ph.D.
Academic staff at First Faculty of Medicine
37 publications
Publications
publication
Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer
2019 |
First Faculty of Medicine
publication
Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition - Mutation Types and their Biological and Clinical Relevance
2019 |
First Faculty of Medicine
publication
Germline mutation in the TP53 gene in uveal melanoma
2018 |
First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma
2015 |
First Faculty of Medicine
publication
Somatic genomic and transcriptomic characterization of primary ovarian serous borderline tumors and low-grade serous carcinomas
2024 |
First Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
publication
A comprehensive molecular analysis of 113 primary ovarian clear cell carcinomas reveals common therapeutically significant aberrations
2023 |
First Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Second Faculty of Medicine, Faculty of Medicine in Pilsen
publication
HER2 status as a potential predictive biomarker for ovarian clear cell carcinoma
2023 |
First Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Second Faculty of Medicine, Faculty of Medicine in Pilsen
publication
Primary Mucinous Tumors of the Ovary: An Interobserver Reproducibility and Detailed Molecular Study Reveals Significant Overlap Between Diagnostic Categories
2023 |
First Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Faculty of Medicine in Pilsen
publication
Microsatellite Instability in Non-Endometrioid Ovarian Epithelial Tumors: A study of 400 cases Comparing Immunohistochemistry, PCR, and NGS Based Testing with Mutation Status of MMR Genes
2023 |
First Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Faculty of Medicine in Pilsen
publication
Refined criteria for p53 expression in ovarian mucinous tumours are highly concordant with TP53 mutation status, but p53 expression/TP53 status lack prognostic significance
2023 |
First Faculty of Medicine, Third Faculty of Medicine, Faculty of Medicine in Hradec Králové, Faculty of Medicine in Pilsen
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