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cytochrome P450 (CYP)
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RNDr. Katarína Vavrová Ph.D.
Academic staff at Faculty of Science
4 publications
Publications
publication
The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib
2022 |
Faculty of Science
publication
Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems
2020 |
Faculty of Science, Second Faculty of Medicine
publication
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity
2020 |
Faculty of Science
publication
Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation
2019 |
Faculty of Science, Second Faculty of Medicine
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