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antiproliferative effect
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PharmDr. Darina Muthná Ph.D.
Academic staff at Faculty of Medicine in Hradec Králové
66 publications
Publications
publication
Semisynthetic derivatives of haemanthamine and their in vitro antiproliferative activity evaluation against a panel of human cell lines
2022 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Pancracine, a Montanine-Type Amaryllidaceae Alkaloid, Inhibits Proliferation of A549 Lung Adenocarcinoma Cells and Induces Apoptotic Cell Death in MOLT-4 Leukemic Cells
2021 |
Faculty of Medicine in Hradec Králové
publication
Anticancer potential of Amaryllidaceae alkaloids evaluated by screening with a panel of human cells, real-time cellular analysis and Ehrlich tumor-bearing mice
2017 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [(eta(6)-p-MeC6H4Pri)(2)Ru-2(mu-S-p-C6H4OH)(3)]Cl
2016 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
Novel caffeine derivatives with antiproliferative activity
2016 |
Faculty of Medicine in Hradec Králové
publication
[(p-MeC6H4Pri)2Ru2(SC6H4-p-But)3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study
2015 |
Faculty of Medicine in Hradec Králové
publication
Boldine and related aporphines: From antioxidant to antiproliferative properties
2013 |
Faculty of Medicine in Hradec Králové
publication
In silico library screening to find novel anticancer agent with chemosensitizing properties: focus on targeting ataxia telangiectasia and Rad3 related kinase
2024 |
Faculty of Medicine in Hradec Králové
publication
Antiproliferative activity and apoptosis-inducing mechanism of Amaryllidaceae alkaloid montanine on A549 and MOLT-4 human cancer cells
2023 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities
2023 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
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